Brand
name: FASIGYN (Tinidazole)
Pronounced: TINi-da-sole
Generic name: Tinidazole
Why is FASIGYN (Tinidazole) prescribed?
FASIGYN (Tinidazole) is prescribed to treat infections caused by a variety of
parasites, including:
* Trichomoniasis, a common sexually transmitted disease that affects
men and women. It can contribute to reduced fertility in both sexes
and may enhance the acquisition and transmission of HIV. Trichomoniasis
has also been linked to cervical cancer, preterm birth, and postoperative
infection. Symptoms in women include yellow or green vaginal discharge
(often with a foul odor) and vaginal burning, itching, soreness or
redness. Urination and intercourse may also be painful. Men who are
infected with trichomoniasis frequently do not have symptoms and often
unknowingly transmit the infection to their partner. When symptoms
are present in men, they may include urethral discharge and irritation.
* Giardiasis, an intestinal infection caused by drinking untreated water. Symptoms
include abdominal pain, nausea, vomiting, diarrhea, cramping, bloating, and
weight loss.
* Intestinal amebiasis (commonly known as dysentery), an infection caused by
consuming contaminated water or food. Symptoms may include loose stools, stomach
pain, and cramping. In more severe cases, symptoms can include severe stomach
pain, weight loss, bloody stools, and fever.
* Amebic liver abscess, a severe and potentially life-threatening infection
caused by the same parasite that causes intestinal amebiasis. Symptoms may
not be detectable. When symptoms do appear, they can include fever, jaundice,
loss of appetite, diarrhea, and intense stomach pain, especially in the upper
right-hand side near the liver.
Most important fact about FASIGYN (Tinidazole) without prescriptions
Do not drink alcohol while taking FASIGYN (Tinidazole) or for 3 days after you
stop taking the drug. Combining alcohol with FASIGYN (Tinidazole) can cause stomach
cramps, nausea, vomiting, headaches, and flushing. When FASIGYN (Tinidazole) is
combined with alcohol and the drug disulfiram (Antabuse), a severe
mental disorder can occur. Always check the labels on foods and over-the-counter
products to make sure they do not contain alcohol.
How should you take FASIGYN (Tinidazole)?
Take FASIGYN (Tinidazole) with food at about the same time each day. The drug
works best when there's a constant amount in the bloodstream.
For people who cannot swallow tablets, a pharmacist can make FASIGYN (Tinidazole)
into a syrup.
If you miss a dose...
Take the forgotten dose as soon as you remember. However, if it is
almost time for your next dose, skip the one you missed and return
to your regular schedule. Do not take two doses at once.
Storage instructions...
Store at room temperature.
FASIGYN (Tinidazole) side effects
Side effects cannot be anticipated. If any develop or change in intensity,
tell your doctor as soon as possible. Only your doctor can determine
if it is safe to continue using FASIGYN (Tinidazole).
* Side effects may include:
Abdominal pain, appetite loss, bitter or metallic taste, confusion, depression,
difficulty breathing, drowsiness, fatigue, headache, loss of consciousness,
nausea, skipped heartbeat, vaginal discharge, vomiting, weakness
Although rare, FASIGYN (Tinidazole) has caused seizures and numbness or tingling
in the arms, hands, legs, and feet (see "Special warnings about
FASIGYN (Tinidazole)").
Why should FASIGYN (Tinidazole) not be prescribed?
Do not use FASIGYN (Tinidazole) if you have ever had an allergic reaction to other
drugs in the same class such as metronidazole (Flagyl).
You should not take FASIGYN (Tinidazole) within 2 weeks of the drug disulfiram
(Antabuse).
FASIGYN (Tinidazole) should not be used during the first 3 months of pregnancy.
Special warnings about FASIGYN (Tinidazole)
Use FASIGYN (Tinidazole) cautiously if you have any disease of the central nervous
system. In rare cases, the drug has caused seizures or peripheral neuropathy
(a painful nerve disorder marked by numbness or tingling in the arms,
hands, legs and feet). If you experience these symptoms, stop taking
FASIGYN (Tinidazole) and call your doctor immediately.
FASIGYN (Tinidazole) can make some medical conditions worse. If you have a blood
disorder, liver disease, or yeast infection, your doctor will monitor
you closely during treatment with FASIGYN (Tinidazole).
If you're taking FASIGYN (Tinidazole) to treat the sexually transmitted disease
trichomoniasis, your partner should be treated at the same time to
prevent you from getting infected again.
Possible food and drug interactions when taking FASIGYN (Tinidazole)
Do not combine FASIGYN (Tinidazole) with alcohol or any product containing alcohol
(see "Most important fact about FASIGYN (Tinidazole)").
If FASIGYN (Tinidazole) is taken with certain other drugs, the effects of either
could be increased, decreased, or altered. It is especially important
to check with your doctor before combining FASIGYN (Tinidazole) with the following:
Blood thinners such as warfarin (Coumadin)
Cholestyramine (Questran, Questran Light)
Cimetidine (Tagamet)
Cyclosporine (Neoral, Sandimmune)
Disulfiram (Antabuse)
Fluorouracil (Adrucil)
Fosphenytoin (Cerebyx)
Ketoconazole (Niz
Special information if you are pregnant or breastfeeding
If you are pregnant or plan to become pregnant, inform your doctor
immediately. FASIGYN (Tinidazole) has not been studied in pregnant women. However,
because lab and animal studies indicate that FASIGYN (Tinidazole) does cross the
placenta, it should not be used during the first 3 months of pregnancy.
FASIGYN (Tinidazole) should only be used in the last 6 months of pregnancy if your
doctor decides the benefits outweigh the risks.
Because FASIGYN (Tinidazole) appears in breast milk, you should not take it while
breastfeeding. If your doctor decides to treat you with FASIGYN (Tinidazole), you'll
have to avoid breastfeeding while you're taking the drug and for 3
days after the last dose.
Recommended dosage for FASIGYN (Tinidazole)
ADULTS
Overdosage
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